Flat Preloader Icon Attendere..
CodeA06209
BrandBoster
TitleHDAC-11 (N-terminus) Polyclonal Antibody
DescriptionHDAC-11 (N-terminus) Polyclonal Antibody
Size100 ug
alternative_nameHistone deacetylase 11
cloneN/A
concentration0.5 mg/mL by UV absorbance at 280 nm
Scheda prodottoLINK
formatN/A
general_informationHistone deacetylase 11 is a 39kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells.
hostRabbit
immunogenN/A
isotypeN/A
protein_idHDAC11
purityN/A
storageAt -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
ApplicationIF
Target speciesHu
HostRabbit
ClassPolyclonal
LabeledUnconjugated