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CodeEK0453
BrandBoster
TitleHuman MIP-3 Alpha/CCL20 PicoKine"! ELISA Kit
DescriptionHuman MIP-3 Alpha/CCL20 PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameC-C motif chemokine 20
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK0453
general_informationMacrophage Inflammatory Protein 3alpha(MIP3alpha), also called Chemokine, cc motif, ligand 20(CCL20). The MIP-3alpha/CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FISH analysis to 2q35-q36. MIP3alpha is predominantly expressed in lymph nodes, appendix, PBL, fetal liver, fetal lung and several cell lines. MIP3alpha/CCL20 and its receptor CCR6 are markedly up-regulated in psoriasis, and they may play a role in the recruitment of T cells to lesional psoriatic skin. And Alanine MIP-3alpha and Serine MIP-3alpha, the two forms of MIP3alpha, that differ by one amino acid at the predicted signal peptide cleavage site. Both of them were chemically synthesized and tested for biological activity. And both flu antigen plus IL-2-activated CD4(+) and CD8(+) T lymphoblasts and cord blood-derived dendritic cells responded to Ser and Ala MIP-3alpha.
protein_idP78556
range_detection7.8pg/ml-500pg/ml
sensitivity<1pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Target speciesHu
Assay typecomplete kit