| Code | EK0535 |
| Brand | Boster |
| Title | Human uPA/PLAU PicoKine"! ELISA Kit |
| Description | Human uPA/PLAU PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Urokinase-type plasminogen activator |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0535 |
| general_information | Plasminogen activator,urokinase(PLAU, uPA) converts plasminogen to plasmin. Plasmin is involved in processing of amyloid precursor protein and degrades secreted and aggregated amyloid-beta, a hallmark of Alzheimer disease(AD). Urokinase has a molecular mass of about 54 kD and is composed of 2 disulfide-linked chains, A and B, of molecular masses 18 kD and 33 kD, respectively. It localized on 10q24. uPA facilitates cell migration by localizing proteolisys on the cell surface and by inducing intracellular signalling pathways. In human vascular smooth muscle cell(VSMC), uPA stimulates migration via the uPA receptor(uPAR) signalling complex containing TYK2 and phosphatidylinositol 3-kinase(PI3-K). |
| protein_id | P00749 |
| range_detection | 62.5pg/ml-4000pg/ml |
| sensitivity | <5pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
| Target species | Hu |
| Assay type | complete kit |
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