Code | EK0537 |
Brand | Boster |
Title | Human VCAM-1 PicoKine"! ELISA Kit |
Description | Human VCAM-1 PicoKine”! ELISA Kit |
Size | 1 x 96T |
alternative_name | Vascular cell adhesion protein 1 |
Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0537 |
general_information | Vascular cell adhesion molecule 1(VCAM-1) is a cell surface glycoprotein adhesive for certain blood leukocytes and tumor cells, which is expressed by activated endothelium in a variety of pathologic conditions including atherosclerosis. Increased expression of VCAM1 is associated with a variety of chronic inflammatory conditions, making its expression and function a target for therapeutic intervention. Integrin alpha4beta1(VLA-4) and VCAM-1 facilitate a critical cell-cell adhesion event required for survival of endothelial and mural cells during vascularization. The VCAM1 gene is assigned to the 1p31-32 region of chromosome 1 based on the analysis of human-mouse hybrid cell lines and in situ hybridization. The standard product used in this kit is recombinant human VCAM-1, consisting of Phe25-Glu698 amino acid sequence of a single chain with the molecular mass of 74KDa. As a result of glycosylation, the molecular mass of 90-95KDa is revealed by SDS-PAGE. |
protein_id | P19320 |
range_detection | 156pg/ml-10,000pg/ml |
sensitivity | <10pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
Target species | Hu |
Assay type | complete kit |