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CodeEK0658
BrandBoster
TitleHuman APP PicoKine"! ELISA Kit
DescriptionHuman APP PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameAmyloid beta A4 protein
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK0658
general_informationAmyloid precursor protein(APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid(Abeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients. APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive.
protein_idP05067
range_detection312pg/ml-20,000pg/ml
sensitivity<100pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, cell lysates, serum and plasma (heparin, EDTA).
Target speciesHu
Assay typecomplete kit