| Code | EK0708 |
| Brand | Boster |
| Title | Mouse B7-1/CD80 PicoKine"! ELISA Kit |
| Description | Mouse B7-1/CD80 PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | T-lymphocyte activation antigen CD80 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0708 |
| general_information | The protein CD80(Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain. The CD80 and CD86(601020) genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. stated that B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4. The standard product used in this kit is recombinant B7-1, D37-K245, which is composed of two single chains acids with the dipolymer. |
| protein_id | Q00609 |
| range_detection | 62.5pg/ml-4000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates and serum. |
| Target species | Mouse |
| Assay type | complete kit |
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