| Code | EK0756 |
| Brand | Boster |
| Title | Human ErbB-2 PicoKine"! ELISA Kit |
| Description | Human ErbB-2 PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Receptor tyrosine-protein kinase erbB-2 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0756 |
| general_information | HER2/neu(also known as ErbB-2) stands for "Hu Epidermal growth factor Receptor 2" and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2/neu has also been designated as CD340(cluster of differentiation 340) and p185. It is encoded by the ERBB2 gene.HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. It is encoded within the genome by HER2/neu, a known proto-oncogene. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. However, ErbB receptors dimerise on ligand binding, and HER2 is the preferential dimerisation partner of other members of the ErbB family.1 The HER2 gene is a proto-oncogene located at the long arm of human chromosome 17(17q21-q22)2. |
| protein_id | P04626 |
| range_detection | 15.6pg/ml-1000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin, EDTA). |
| Target species | Hu |
| Assay type | complete kit |
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