| Code | EK0811 |
| Brand | Boster |
| Title | Mouse Mer PicoKine"! ELISA Kit |
| Description | Mouse Mer PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Tyrosine-protein kinase Mer |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0811 |
| general_information | Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type(immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium(RPE) as a regulator of rod outer segments fragments phagocytosis. This gene also plays an important role in inhibition of Toll-like receptors(TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. |
| protein_id | Q60805 |
| range_detection | 78pg/ml-5000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, cell lysates and serum. |
| Target species | Mouse |
| Assay type | complete kit |
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