| Code | EK0941 |
| Brand | Boster |
| Title | Human MIA PicoKine"! ELISA Kit |
| Description | Human MIA PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Melanoma-derived growth regulatory protein |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0941 |
| general_information | Melanoma Inhibiting Activity(MIA), also known as cartilage-derived retinoic acid-sensitive protein(CD-RAP), is an approximately 11-15 kDa protein that is expressed as a noncovalent homodimer. MIA is structurally related to OTOR/Otoraplin and MIA-2 in a small family of secreted proteins with one SH3 domain(1-3). And the MIA gene was mapped to 19q13.32-q13.33 by fluorescence in situ hybridization. Beside, It is a marker for malignant melanoma. MIA functions as a chemoattractant for mesenchymal stem cells and enhances their BMP-2 and TGF-beta3 induced differentiation into chondrocytes . MIA-deficient mice exhibit delayed chondrocyte differentiation but enhanced chondrocyte proliferation and cartilage repair . |
| protein_id | Q16674 |
| range_detection | 15.6pg/ml-1000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum, plasma(heparin, EDTA) and saliva. |
| Target species | Hu |
| Assay type | complete kit |
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