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CodeMA1080
BrandBoster
TitlePaxillin Monoclonal Antibody
DescriptionPaxillin Monoclonal Antibody
Size100 ug
clonePAX-14
concentrationN/A
Scheda prodottoLINK
formatWhole IgG
general_informationThe paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.
hostMouse
immunogenC-terminal part of recombinant chicken paxillin (amino acids 305-559).
isotypeIgG1
Secondary antibodiesLINK
protein_idHu(P49023), Mouse(Q8VI36), Rat(Q66H76)
purityAffinity purified
storage"At -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing. "
ApplicationWB, ICC
Target speciesHu, Ms, Rt, Ck
HostMouse
ClassMonoclonal
LabeledUnconjugated