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CodeEK0449
BrandBoster
TitleMouse MIP-1Alpha/CCL3 PicoKine"! ELISA Kit
DescriptionMouse MIP-1Alpha/CCL3 PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameC-C motif chemokine 3
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK0449
general_informationChemokine(C-C motif) ligand 3(CCL3), so known as Macrophage inflammatory protein-1alpha(MIP-1 alpha), is a protein that in humans is encoded by the CCL3 gene. It is a cytokine which belongs to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. This gene is mapped to 17q12. CCL3 plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. It has been found that the activation of CCR5 by CCL3 directly and independently activates a G-protein signaling pathway through GNAI2 and a tyrosine phosphorylation signaling pathway through JAK2.
protein_idP10855
range_detection7.8pg/ml-500pg/ml
sensitivity<10pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin, EDTA, citrate).
Target speciesMouse
Assay typecomplete kit