| Code | EK0845 |
| Brand | Boster |
| Title | Mouse TREM-1 PicoKine"! ELISA Kit |
| Description | Mouse TREM-1 PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Triggering receptor expressed on myeloid cells 1 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0845 |
| general_information | Trem1, Triggering receptor expressed on myeloid cells-1, is encoded by Trem1 gene. The expression of Trem1 is in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. Trem1 is a 30-kD glycoprotein that is reduced to 26 kD by deglycosylation, in agreement with the predicted molecular mass. The Trem1 gene which contains 4 exons maps to chromosome 6p21.1, within a TREM gene cluster and the mouse Trem1 gene maps to chromosome 17 in a region that shows homology of synteny to human chromosome 6. The expression of Trem1 is upregulated by stimulation with lipopolysaccharide(LPS), gram-negative bacteria, and fungi. Cross-linking of Trem1 on neutrophils induces interleukin-8(IL8) and myeloperoxidase secretion, while cross-linking on monocytes induces not only secretion of IL8 but also of monocyte chemotactic protein-1(MCP1, or SCYA2) and tumor necrosis factor(TNF) |
| protein_id | Q9JKE2 |
| range_detection | 31.2pg/ml-2000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum, plasma(heparin, EDTA) and cell lysates. |
| Target species | Mouse |
| Assay type | complete kit |
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