Code | EK1428 |
Brand | Boster |
Title | Human Relaxin 2 PicoKine"! ELISA Kit |
Description | Human Relaxin 2 PicoKine”! ELISA Kit |
Size | 1 x 96T |
alternative_name | Prorelaxin H2 |
Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1428 |
general_information | Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The active form of the protein encoded by this gene consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. Relaxin 2(RLN2) is a polypeptide hormone structurally related to insulin and insulin-like growth factors (IGFs). However it does not interact with insulin receptors and has decidedly different biological properties. Relaxin 2 activates LGR 7 and LGR 8 relaxin receptors, that belong to the leucine-rich repeat-containing (LRR), G protein-coupled receptors. |
protein_id | P04090 |
range_detection | 7.8pg/ml-500pg/ml |
sensitivity | <4pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
Target species | Hu |
Assay type | complete kit |