| Code | EK1433 |
| Brand | Boster |
| Title | Mouse EGFR PicoKine"! ELISA Kit |
| Description | Mouse EGFR PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Epidermal growth factor receptor |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1433 |
| general_information | The epidermal growth factor receptor (EGFR |
| HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. It is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases | EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). EGFR exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor α (TGFα). EGFR and its ligands are cell signaling molecules involved in diverse cellular functions, including cell proliferation, differentiation, motility, and survival, and in tissue development. Mutations that lead to EGFR overexpression (known as upregulation) or overactivity have been associated with a number of cancers, including lung cancer and glioblastoma multiforme. In this latter case a more or less specific mutation of EGFR, called EGFRvIII is often observed. |
| protein_id | Q01279 |
| range_detection | 156pg/ml-10000pg/ml |
| sensitivity | <15pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
| Target species | Mouse |
| Assay type | complete kit |
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