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CodeA06179
BrandBoster
TitleAP2M1 Polyclonal Antibody
DescriptionAP2M1 Polyclonal Antibody
Size100 ug
alternative_nameAdaptin mu 1 | Adaptin-mu2 | AP 2 mu 2 chain | AP-2 complex subunit mu | Ap2m1 | AP50 | CLAPM1 | Q96CW1
cloneN/A
concentrationN/A
Scheda prodottoLINK
formatWhole IgG
general_informationAP-2 complex subunit mu is a protein that in humans is encoded by the AP2M1 gene. This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.
hostRabbit
immunogenA synthetic peptide corresponding to a sequence at the C-terminus of human AP2M1 (399-435aa LKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC), identical to the related mouse and rat sequences.
isotypeIgG
Secondary antibodiesLINK
protein_idQ96CW1
purityImmunogen affinity purified.
storageAt -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing.
ApplicationWB
Target speciesHu, Ms, Rt
HostRabbit
ClassPolyclonal
LabeledUnconjugated