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CodeA07203
BrandBoster
TitleAPEX2 Polyclonal Antibody
DescriptionAPEX2 Polyclonal Antibody
Size100 ug
alternative_nameAP endonuclease XTH2 | APE2 | APE2 | XTH2 | APEX nuclease-like 2 | APEX2 | APEXL 2 | APEXL2 | Q9UBZ4 | XTH 2
cloneN/A
concentrationN/A
Scheda prodottoLINK
formatWhole IgG
general_informationAPEX2, also called apurinic/apyrimidinic endonuclease like-2, is a member of the apurinic/apyrimidinic (AP) family of endonucleases that initiate the repair of AP sites formed by spontaneous hydrolysis of the N-glycosylic bond, mutagen-induced base release, or damaged-base excision by a DNA repair glycosylase. RT-PCR detected APEX2 expression in HeLa cells, Jurkat cells, and human kidney, brain and fetal brain tissue. The APEX2 gene is mapped to chromosome Xp11.21. APEX2 participates in both nuclear and mitochondrial base excision repair (BER) and it can play a role in processing 3-prime-damaged termini or 3-prime-mismatched nucleotides. Additionally, APEX2 displayed weaker AP site-specific and 3-prime nuclease activities compared to APEX1.
hostRabbit
immunogenE.coli-derived human APEX2 recombinant protein (Position
isotypeIgG
Secondary antibodiesLINK
protein_idQ9UBZ4
purityImmunogen affinity purified.
storageAt -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing.
ApplicationWB
Target speciesRt Predicted to work with
HostRabbit
ClassPolyclonal
LabeledUnconjugated