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CodeA05556
BrandBoster
TitleDYNLT1 Picoband™ Polyclonal Antibody
DescriptionDYNLT1 Picoband™ Polyclonal Antibody
Size100 µg
alternative_nameDynein light chain Tctex-type 1
cloneN/A
concentrationN/A
Scheda prodottoLINK
formatWhole IgG
general_informationDynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene. This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
hostRabbit
immunogenE. coli-derived human DYNLT1 recombinant protein (Position
isotypeIgG
Secondary antibodiesLINK
protein_idP63172
storageAt -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
ApplicationELISA, IHC-P, WB
Target speciesHu, Ms, Rt
HostRabbit
ClassPolyclonal
LabeledUnconjugated