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CodeEK0981-PR
BrandBoster
TitleMonkey primate TGF-Beta 2 PicoKine"! ELISA Kit
DescriptionMonkey primate TGF-Beta 2 PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameTransforming growth factor beta-2
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK0981-PR
general_informationTransforming growth factor-beta 2(TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma(POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured monkey primate anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.
protein_idP61812
range_detection31.2pg/ml-2000pg/ml
sensitivity<10pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin, EDTA, citrate).
Target speciesMonkey
Assay typecomplete kit