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CodeEK1651
BrandBoster
TitleRat CXCL4/PF4 PicoKine™ ELISA Kit
DescriptionRat CXCL4/PF4 PicoKine™ ELISA Kit
Size1 x 96T
alternative_namePlatelet factor 4
Scheda prodottoLINK
general_informationPlatelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). The PF4 gene was localized on 4q12-q13. Chemokines play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.
protein_idP06765
range_detection156pg/ml-10000pg/ml
sensitivity<15pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma (heparin, EDTA).
Target speciesRat
Assay typecomplete kit