| Code | EK0759 |
| Brand | Boster |
| Title | Human FGF23 PicoKine"! ELISA Kit |
| Description | Human FGF23 PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Fibroblast growth factor 23 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0759 |
| general_information | Fibroblast growth factor 23 or FGF23 is a protein that in humans is encoded by the FGF23 gene. It is a member of the fibroblast growth factor (FGF) family which is responsible for phosphate metabolism. The main function of FGF23 seems to be regulation of phosphate concentration in plasma. FGF23 is secreted by Osteocytes in response to elevated Calcitriol. And it acts on the kidneys, where it decreases the expression of NPT2, a sodium-phosphate cotransporter in the proximal tubule. Thus, FGF23 decreases the reabsorption and increases excretion of phosphate. Also, FGF23 may suppress 1-alpha-hydroxylase, reducing its ability to activate vitamin D and subsequently impairing calcium absorption. |
| protein_id | Q9GZV9 |
| range_detection | 15.6pg/ml-1000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma (heparin, EDTA). |
| Target species | Hu |
| Assay type | complete kit |
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