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CodeEK1536
BrandBoster
TitleHuman Nectin-4/PVRL4 PicoKine"! ELISA Kit
DescriptionHuman Nectin-4/PVRL4 PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameNectin-4
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK1536
general_informationNectin-4, also known as PVRL4, is an adhesion receptor of the immunoglobulin superfamily and functions in cell-cell adhesion. This gene is mapped to chromosome 1q23.3. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
protein_idQ96NY8
range_detection31.2pg/ml-2000pg/ml
sensitivity<10pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum, plasma(heparin, EDTA), cell lysates and urine.
Target speciesHu
Assay typecomplete kit