| Code | EK0352 |
| Brand | Boster |
| Title | Human FLT3/FLK2 PicoKine ELISA Kit |
| Description | Human FLT3/FLK2 PicoKine ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Receptor-type tyrosine-protein kinase FLT3 |
| concentration | N/A |
| Scheda prodotto | LINK |
| general_information | Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. It is mapped to 13q12.2. This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. |
| protein_id | P36888 |
| range_detection | 62.5pg/ml-4000pg/ml |
| sensitivity | <50pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin). |
| Target species | Hu |
| Target_ig | N/A |
| Assay type | complete kit |
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