| Code | EK1668 |
| Brand | Boster |
| Title | Human CDCP1 PicoKine ELISA Kit |
| Description | Human CDCP1 PicoKine ELISA Kit |
| Size | 1 x 96T |
| alternative_name | CUB domain-containing protein 1 |
| concentration | N/A |
| Scheda prodotto | LINK |
| general_information | CUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene. It has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases). CDCP1/Trask is a 140 kD transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains, and a smaller intracellular domain (ICD) containing five tyrosines. The tyrosine phosphorylation of Trask is tightly regulated and reciprocally linked with the state of cell adhesion. The tyrosine phosphorylation of CDCP1 in cultured cells occurs when cells are induced to detach by trypsin or EDTA, or seen spontaneously during mitotic detachment. The overexpression of CDCP1 leads to the loss of cell adhesion and a detached phenotype. CDCP1 is widely expressed in human epithelial tissues, but its phosphorylation is only seen in mitotically detached or shedding cells, consistent with its role in the negative regulation of cell adhesion. |
| protein_id | Q9H5V8 |
| range_detection | 31.2pg/ml-2000pg/ml |
| sensitivity | <2pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin). |
| Target species | Hu |
| Target_ig | N/A |
| Assay type | complete kit |
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