| Code | EK1765 |
| Brand | Boster |
| Title | Human PAM PicoKine ELISA Kit |
| Description | Human PAM PicoKine ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Peptidyl-glycine alpha-amidating monooxygenase |
| Peptidylglycine alpha-hydroxylating monooxygenase (EC | 1.14.17.3) |
| Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC | 4.3.2.5) |
| concentration | N/A |
| Scheda prodotto | LINK |
| general_information | Peptidyl-glycine alpha-amidating monooxygenase is an enzyme that catalyzes the biosynthesis of many signaling peptides and, in humans, is encoded by the PAM gene. It is mapped to 5q21.1. This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| protein_id | P19021 |
| range_detection | 312pg/ml-20000pg/ml |
| sensitivity | <50pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin). |
| Target species | Hu |
| Target_ig | N/A |
| Assay type | complete kit |
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