Flat Preloader Icon Attendere..
CodeEK2004
BrandBoster
TitleHuman TNFRSF21/DR6 PicoKine ELISA Kit
DescriptionHuman TNFRSF21/DR6 PicoKine ELISA Kit
Size1 x 96T
alternative_nameTumor necrosis factor receptor superfamily member 21
concentrationN/A
Scheda prodottoLINK
general_informationDeath receptor 6 (DR6), also known as tumor necrosis factor receptor superfamily member 21 (TNFRSF21), is a cell surface receptor of the tumor necrosis factor receptor superfamily which activates the JNK and NF-º B pathways. This gene is mapped to 6p12.3. This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
protein_idO75509
range_detection15.6pg/ml-1000pg/ml
sensitivity<10pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target speciesHu
Target_igN/A
Assay typecomplete kit