Code | EK2004 |
Brand | Boster |
Title | Human TNFRSF21/DR6 PicoKine ELISA Kit |
Description | Human TNFRSF21/DR6 PicoKine ELISA Kit |
Size | 1 x 96T |
alternative_name | Tumor necrosis factor receptor superfamily member 21 |
concentration | N/A |
Scheda prodotto | LINK |
general_information | Death receptor 6 (DR6), also known as tumor necrosis factor receptor superfamily member 21 (TNFRSF21), is a cell surface receptor of the tumor necrosis factor receptor superfamily which activates the JNK and NF-º B pathways. This gene is mapped to 6p12.3. This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. |
protein_id | O75509 |
range_detection | 15.6pg/ml-1000pg/ml |
sensitivity | <10pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, serum and plasma(heparin). |
Target species | Hu |
Target_ig | N/A |
Assay type | complete kit |