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CodeEK2069
BrandBoster
TitleHuman GFRA1 PicoKine ELISA Kit
DescriptionHuman GFRA1 PicoKine ELISA Kit
Size1 x 96T
alternative_nameGDNF family receptor alpha-1
concentrationN/A
Scheda prodottoLINK
general_informationGDNF family receptor alpha-1 (GFR± 1), also known as the GDNF receptor, is a protein that in humans is encoded by the GFRA1 gene. It is mapped to 10q25.3. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
protein_idP56159
range_detection46.9pg/ml-3000pg/ml
sensitivity<20pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target speciesHu
Target_igN/A
Assay typecomplete kit