| Code | EK2071 |
| Brand | Boster |
| Title | Rat GFRA1 PicoKine ELISA Kit |
| Description | Rat GFRA1 PicoKine ELISA Kit |
| Size | 1 x 96T |
| alternative_name | GDNF family receptor alpha-1 |
| concentration | N/A |
| Scheda prodotto | LINK |
| general_information | GDNF family receptor alpha-1 (GFR± 1), also known as the GDNF receptor, is a protein that in humans is encoded by the GFRA1 gene. It is mapped to 1q55. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.GDNF family receptor alpha 1 has been shown to interact with GDNF[8][9] and RET proto-oncogene. |
| protein_id | Q62997 |
| range_detection | 15.6pg/ml-1000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin). |
| Target species | Rat |
| Target_ig | N/A |
| Assay type | complete kit |
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