Code | EK2072 |
Brand | Boster |
Title | Human GFRA2 PicoKine ELISA Kit |
Description | Human GFRA2 PicoKine ELISA Kit |
Size | 1 x 96T |
alternative_name | GDNF family receptor alpha-2 |
concentration | N/A |
Scheda prodotto | LINK |
general_information | GDNF family receptor alpha-2 (GFR± 2), also known as the neurturin receptor, is a protein that in humans is encoded by the GFRA2 gene. It is mapped to 8p21.3. The GFRA2 protein is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. They both bind the GFRA2 receptor. The receptor mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. GFRA2 (gene) has been shown to interact with GDNF. |
protein_id | O00451 |
range_detection | 312pg/ml-20000pg/ml |
sensitivity | <50pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, serum and plasma(heparin). |
Target species | Hu |
Target_ig | N/A |
Assay type | complete kit |