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CodeEK2074
BrandBoster
TitleRat GFRA2 PicoKine ELISA Kit
DescriptionRat GFRA2 PicoKine ELISA Kit
Size1 x 96T
alternative_nameGDNF family receptor alpha
concentrationN/A
Scheda prodottoLINK
general_informationGDNF family receptor alpha-2 (GFR± 2), also known as the neurturin receptor, is a protein that in humans is encoded by the GFRA2 gene. It is mapped to 15p11. The GFRA2 protein is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. They both bind the GFRA2 receptor. The receptor mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. GFRA2 (gene) has been shown to interact with GDNF.
protein_idO35977
range_detection312pg/ml-20000pg/ml
sensitivity<50pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target speciesRat
Target_igN/A
Assay typecomplete kit