Rat Legumain PicoKine ELISA Kit

Code	EK2100
Brand	Boster
Title	Rat Legumain PicoKine ELISA Kit
Description	Rat Legumain PicoKine ELISA Kit
Size	1 x 96T
alternative_name	Legumain
concentration	N/A
Scheda prodotto	LINK
general_information	Legumain is a protein that in humans is encoded by the LGMN gene. It is mapped to 6q32. This gene encodes a cysteine protease, legumain, that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.
protein_id	Q9R0J8
range_detection	31.2pg/ml-2000pg/ml
sensitivity	<10pg/ml
storage	Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection method	ELISA
Sample Type	cell culture supernates, serum and plasma(heparin).
Target species	Rat
Target_ig	N/A
Assay type	complete kit