Anti-Claudin 7/CLDN-7 Polyclonal Antibody

Code	A03851-2
Brand	Boster
Title	Anti-Claudin 7/CLDN-7 Polyclonal Antibody
Description	Anti-Claudin 7/CLDN-7 Polyclonal Antibody
Size	100ug
alternative_name	Cldn7
clone	N/A
concentration	N/A
Scheda prodotto	LINK
format	Rabbit IgG
general_information	Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.
host	Rabbit
isotype	IgG
Secondary antibodies	LINK
protein_id	Q9Z261
storage	At -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing.
Application	WB
Target_ig	mouse
Host	Rabbit
Class	Polyclonal
Labeled	Unconjugated