Annexin A1 Polyclonal Antibody

Code	PA1006
Brand	Boster
Title	Annexin A1 Polyclonal Antibody
Description	Annexin A1 Polyclonal Antibody
Size	100 ug
alternative_name	Annexin A1
clone	N/A
concentration	N/A
Scheda prodotto	LINK
format	Whole IgG
general_information	Annexin I, also known as lipocortin I (Lipo1), belongs to the family of annexins. These proteins are thought to control the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes. In two lipocortins (I and II) a short amino-terminal sequence distinct from the core structure has potential regulatory functions which are dependent on its phosphorylation state. The gene in the mouse encodes a protein of 346 amino acid residues. Mouse Lipo1 gene spans about 17 kb and is divided into 13 exons. Annexin I gene, mapped to 9q11-q22, is located on mouse chromosome 19. Annexin I acts through the formyl peptide receptor on human neutrophils. Peptides derived from the unique N-terminal domain of annexin I serve as FPR ligands and trigger different signaling pathways in a dose-dependent manner.
host	Rabbit
immunogen	A synthetic peptide corresponding to a sequence at the N-terminal of human Annexin I.
isotype	IgG
Secondary antibodies	LINK
protein_id_url	LINK
purity	Affinity purified
storage	"At -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing. "
Application	WB, IHC-P
Target species	Hu
Host	Rabbit
Class	Polyclonal
Labeled	Unconjugated