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CodeA06146
BrandBoster
TitleAnti-AMD1/Adometdc Polyclonal Antibody
DescriptionAnti-AMD1/Adometdc Polyclonal Antibody
Size100ug
alternative_nameS-adenosylmethionine decarboxylase proenzyme
cloneN/A
concentrationN/A
Scheda prodottowww.bosterbio.com/datasheet.php?sku=A06146
formatWhole IgG
general_informationS-adenosylmethionine decarboxylase (AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC) or AMD1, is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.
hostRabbit
isotypeIgG
Secondary antibodiesLINK
protein_id_urlAMD1
storageAt -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
ApplicationIHC, WB
HostRabbit
ClassPolyclonal
LabeledUnconjugated