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CodeA03851-3
BrandBoster
TitleAnti-Claudin 7/CLDN-7 Antibody
DescriptionAnti-Claudin 7/CLDN-7 Antibody
Size1 x 96T
alternative_nameCLDN7
concentrationN/A
Scheda prodottoLINK
formatRabbit IgG
general_informationClaudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.
hostRabbit IgG
protein_idO95471
range_detection312pg/ml-20000pg/ml
sensitivity<10pg/ml
storageStore at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.(Shipped with wet ice.)
Detection methodELISA
ApplicationIHC-P,FCM,Direct ELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target speciesHu
Target_igReacts with
HostRabbit IgG
Assay typecomplete kit