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CodeA06941-1
BrandBoster
TitleAnti-MAL Polyclonal Antibody
DescriptionAnti-MAL Polyclonal Antibody
Size100ug
alternative_nameTIRAP
cloneN/A
concentrationN/A
Scheda prodottoLINK
formatRabbit IgG
general_informationMyelin and lymphocyte protein is a protein that in humans is encoded by the MAL gene. The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.
hostRabbit
isotypeIgG
Secondary antibodiesLINK
protein_idP21145
storageAt -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing.
ApplicationWB
Target_ighuman
HostRabbit
ClassPolyclonal
LabeledUnconjugated