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CodePA1366
BrandBoster
TitleCDC42 Polyclonal Antibody
DescriptionCDC42 Polyclonal Antibody
Size100 ug
alternative_nameCell division control protein 42 homolog(Cdc42 homolog)
cloneN/A
concentrationN/A
Scheda prodottoLINK
formatWhole IgG
general_informationCell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene.CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
hostRabbit
immunogenA synthetic peptide corresponding to a sequence in the middle region of human CDC42, identical to the related mouse and rat sequence.
isotypeIgG
Secondary antibodiesLINK
protein_id_urlLINK
purityAffinity purified
storage"At -20Ú C for one year. After reconstitution, at 4Ú C for one month. It can also be aliquotted and stored frozen at -20Ú C for a longer time. Avoid repeated freezing and thawing. "
ApplicationWB,IHC-P
Target speciesHu, Ms, Rt, Bv
HostRabbit
ClassPolyclonal
LabeledUnconjugated