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CodeM64001-1
BrandEpigentek
TitleChaetocin
DescriptionChaetocin
Size200 ug
Scheda prodottoLINK
formatN/A
hostN/A
id_area_ricerca34
notesChaetocin, an antitumor antibiotic, is a thiodioxopiperazine natural product produced by Chaetomium species. Specific inhibitor of the lysine-specific methyltransferase SU (VAR)3-9 both in vitro and in vivo. It displays potent antimyeloma activity in IL-6-dependent myeloma cell lines. Its antimyeloma activity appears to be due to induction of oxidative stress and consequent apoptosis
research_areaEpigenetics
storagesee data sheet
ApplicationLys-specific methyltrasferase inhibitor
Target speciesN/A
HostN/A