Flat Preloader Icon Attendere..
CodeA05478
BrandBoster
TitleHtrA3 Polyclonal Antibody
DescriptionHtrA3 Polyclonal Antibody
Size100 ug
alternative_nameHTRA3 | PRSP | Tasp | P83110
cloneN/A
concentrationAdd 0.2ml of distilled water will yield a concentration of 500ug/ml.
Scheda prodottoLINK
formatN/A
general_informationHu HtrA3 protease, which induces mitochondria-mediated apoptosis, can be a tumor suppressor and a potential therapeutic target in the treatment of cancer. It may also have a role in ovarian development, granulosa cell differentiation and luteinization. The long isoform, HTRA3L, contains 453 amino acids and has a predicted molecular mass of 49 kD. It contains an N-terminal signal peptide, followed by an insulin/IGF (see 147440)-binding domain, a Kazal-type S protease inhibitor domain, a trypsin protease domain, and a PDZ domain. The short isoform, HTRA3S, contains 357 amino acids and has a predicted molecular mass of 38 kD.
hostRabbit
immunogenA synthetic peptide corresponding to a sequence at the C-terminus of human HtrA3 (330-362aa FAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMR), different from the related mouse sequence by four amino acids, and from the related rat sequence by three amino acids.
isotypeN/A
protein_idHTRA3
purityImmunogen affinity purified.
storageAt -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
ApplicationWB
Target speciesHu
HostRabbit
ClassPolyclonal
LabeledUnconjugated