| Code | EK1446 |
| Brand | Boster |
| Title | Human ADA/Adenosine Deaminase PicoKine"! ELISA Kit |
| Description | Human ADA/Adenosine Deaminase PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Adenosine deaminase |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1446 |
| general_information | Adenosine Deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. ADA in humans is involved in the development and maintenance of the immune system. However, ADA association has also been observed with epithelial cell differentiation, neurotransmission, and gestation maintenance. It has also been proposed that ADA, in addition to adenosine breakdown, stimulates release of excitatory amino acids and is necessary to the coupling of A1 adenosine receptors and heterotrimeric G proteins. Adenosine deaminase deficiency leads to pulmonary fibrosis, suggesting that chronic exposure to high levels of adenosine can exacerbate inflammation responses rather than suppressing them. It has also been recognized that adenosine deaminase protein and activity is upregulated in mouse hearts that overexpress HIF-1 alpha, which in part explains the attenuated levels of adenosine in HIF-1 alpha expressing hearts during ischemic stress. |
| protein_id | P00813 |
| range_detection | 31.2pg/ml-2000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and pleural fluid. |
| Target species | Hu |
| Assay type | complete kit |
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