| Code | EK1869 |
| Brand | Boster |
| Title | Human AKR1C3 PicoKine ELISA Kit |
| Description | Human AKR1C3 PicoKine ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Aldo-keto reductase family 1 member C3 (EC |
| 3-alpha-hydroxysteroid dehydrogenase type 2 (EC | 1.1.1.357) |
| Indanol dehydrogenase (EC | 1.1.1.112) |
| Prostaglandin F synthase (EC | 1.1.1.188) |
| Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC | 1.3.1.20) |
| concentration | N/A |
| Scheda prodotto | LINK |
| general_information | Aldo-keto reductase family 1 member C3 (AKR1C3), also known as 17² -hydroxysteroid dehydrogenase type 5 (17² -HSD5, HSD17B5) is a key steroidogenic enzyme that in humans is encoded by the AKR1C3 gene. It is mapped to 10p15.1. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. |
| protein_id | P42330 |
| range_detection | 15.6pg/ml-1000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin). |
| Target species | Hu |
| Target_ig | N/A |
| Assay type | complete kit |
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