Code | FEK0707 |
Brand | Boster |
Title | Human B7-1/CD80 PicoKine™ Fast ELISA Kit |
Description | Human B7-1/CD80 PicoKine™ Fast ELISA Kit |
Size | 1 x 96T |
alternative_name | T-lymphocyte activation antigen CD80 |
concentration | N/A |
Scheda prodotto | LINK |
general_information | The protein CD80(Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7-1. The cDNA for B7-1 predicts a type I membrane protein, i.e., one synthesized with a signal peptide that is cleaved upon translocation across the endoplasmic membrane. The protein is predicted to contain 2 extracellular domains structurally similar to those of Ig, a hydrophobic transmembrane region, and a short cytoplasmic domain. The CD80 and CD86 genes encode B7-1 and B7-2, respectively, which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4. |
protein_id | P33681 |
range_detection | 62.5pg/ml-4000pg/ml |
sensitivity | <10pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, serum and plasma(heparin). |
Target species | Hu |
Target_ig | N/A |
Assay type | complete kit |