| Code | EK1425 |
| Brand | Boster |
| Title | Human Caspase 3 PicoKine"! ELISA Kit |
| Description | Human Caspase 3 PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Caspase-3 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1425 |
| general_information | Caspase-3 is a caspase protein that is encoded by the CASP3 gene. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. |
| protein_id | P42574 |
| range_detection | 31.2pg/ml-2000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernate sand serum. |
| Target species | Hu |
| Assay type | complete kit |
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