Code | EK0735 |
Brand | Boster |
Title | Human CXCL10/IP-10 PicoKine"! ELISA Kit |
Description | Human CXCL10/IP-10 PicoKine”! ELISA Kit |
Size | 1 x 96T |
alternative_name | C-X-C motif chemokine 10 |
Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0735 |
general_information | Chemokine(C-X-C motif) ligand 10(CXCL10) or IP-10 is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein(gamma-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-gamma. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis.It is a potent inhibitor of angiogenesis in vivo. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. It is a RAS target gene and is overexpressed in the majority of colorectal cancers.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3. |
protein_id | P02778 |
range_detection | 31.2pg/ml-2000pg/ml |
sensitivity | <1pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, serum, plasma(heparin, EDTA), saliva and urine. |
Target species | Hu |
Assay type | complete kit |