| Code | EK2064 |
| Brand | Boster |
| Title | Human Elastase/ELANE/ELA2 PicoKine ELISA Kit |
| Description | Human Elastase/ELANE/ELA2 PicoKine ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Neutrophil elastase |
| concentration | N/A |
| Scheda prodotto | LINK |
| general_information | In humans, neutrophil elastase is encoded by the ELANE gene, which resides on chromosome 19. It is mapped to 19p13.3. Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Hus have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. |
| protein_id | P08246 |
| range_detection | 0.78ng/ml-50ng/ml |
| sensitivity | <50pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin). |
| Target species | Hu |
| Target_ig | N/A |
| Assay type | complete kit |
Attendere..
