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CodeEK0329
BrandBoster
TitleHuman Eotaxin PicoKine"! ELISA Kit
DescriptionHuman Eotaxin PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameEotaxin
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK0329
general_informationEotaxin, also known as CCL11, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3(CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. Eotaxin is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. The deduced mature protein sequence is 66% identical to human monocyte chemoattractant protein-1, and 60% identical to guinea pig eotaxin. Recombinant human eotaxin produced in insect cells induces a calcium flux response in normal human eosinophils, but not in neutrophils or monocytes. The human eotaxin gene is cloned and found to be 61.8 and 63.2% identical at the amino acid level to guinea pig and mouse eotaxin.
protein_idP51671
range_detection15.6pg/ml-1000pg/ml
sensitivity<2pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(citrate, EDTA).
Target speciesHu
Assay typecomplete kit