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CodeFEK0337
BrandBoster
TitleHuman FASL / CD95 PicoKine™ Fast ELISA Kit
DescriptionHuman FASL / CD95 PicoKine™ Fast ELISA Kit
Size1 x 96T
alternative_nameTumor necrosis factor ligand superfamily member 6
concentrationN/A
Scheda prodottoLINK
general_informationFas ligand(FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor(TNF) family. Its binding with its receptor induces apoptosis. The human FASL gene consists of approximately 8 kb and is split into 4 exons. Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer. Fas ligand or FasL is a homotrimeric type II transmembrane protein. It signals through trimerization of FasR, which spans the membrane of the "target" cell. This trimerization usually leads to apoptosis, or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external matrix metalloproteinase MMP-7.
protein_idP48023
range_detection15.6pg/ml-1000pg/ml
sensitivity<2pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma(heparin).
Target speciesHu
Target_igN/A
Assay typecomplete kit