| Code | EK0337 |
| Brand | Boster |
| Title | Human FASL PicoKine"! ELISA Kit |
| Description | Human FASL PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Tumor necrosis factor ligand superfamily member 6 |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0337 |
| general_information | Fas ligand(FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor(TNF) family. Its binding with its receptor induces apoptosis. The human FASL gene consists of approximately 8 kb and is split into 4 exons. Fas ligand/receptor interactions play an important role in the regulation of the immune system and the progression of cancer. Fas ligand or FasL is a homotrimeric type II transmembrane protein. It signals through trimerization of FasR, which spans the membrane of the "target" cell. This trimerization usually leads to apoptosis, or cell death. Soluble Fas ligand is generated by cleaving membrane-bound FasL at a conserved cleavage site by the external matrix metalloproteinase MMP-7. |
| protein_id | P48023 |
| range_detection | 15.6pg/ml-1000pg/ml |
| sensitivity | <2pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, serum and plasma(heparin, EDTA, citrate). |
| Target species | Hu |
| Assay type | complete kit |
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