| Code | EK1431 |
| Brand | Boster |
| Title | Human Hepcidin PicoKine"! ELISA Kit |
| Description | Human Hepcidin PicoKine”! ELISA Kit |
| Size | 1 x 96T |
| alternative_name | Hepcidin |
| Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK1431 |
| general_information | Hepcidin is a protein that in humans is encoded by the HAMP gene. The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. |
| protein_id | P81172 |
| range_detection | 15.6pg/ml-1000pg/ml |
| sensitivity | <10pg/ml |
| storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
| Detection method | ELISA |
| Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
| Target species | Hu |
| Assay type | complete kit |
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