Code | EK0784 |
Brand | Boster |
Title | Human IL-17RA PicoKine"! ELISA Kit |
Description | Human IL-17RA PicoKine”! ELISA Kit |
Size | 1 x 96T |
alternative_name | Interleukin-17 receptor A |
Scheda prodotto | www.bosterbio.com/datasheet.php?sku=EK0784 |
general_information | Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene. The IL17R gene is mapped to 22q11.22-q11.23 by radiation hybrid analysis. Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Also, it is showed that mouse Il17r bound HSV-13 and mouse Il17. Recombinant soluble Il17r inhibited mitogen-induced T-cell proliferation and Il2 production. |
protein_id | Q96F46 |
range_detection | 31.2pg/ml-2000pg/ml |
sensitivity | <10pg/ml |
storage | Store at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.) |
Detection method | ELISA |
Sample Type | cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
Target species | Hu |
Assay type | complete kit |