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CodeEK0468
BrandBoster
TitleHuman MMP13 PicoKine"! ELISA Kit
DescriptionHuman MMP13 PicoKine”! ELISA Kit
Size1 x 96T
alternative_nameCollagenase 3
Scheda prodottowww.bosterbio.com/datasheet.php?sku=EK0468
general_informationCollagenase 3 is an enzyme that in humans is encoded by the MMP13 gene. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. The expression of MMP13 in osteoarthritic cartilage and its activity against type II collagen indicates that the enzyme plays a significant role in cartilage collagen degradation and must, therefore, form part of a complex target for proposed therapeutic interventions based on collagenase inhibition. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
protein_idA8K846
range_detection156pg/ml-10,000pg/ml
sensitivity<5pg/ml
storageStore at 4Ú C for 6 months, at -20Ú C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Detection methodELISA
Sample Typecell culture supernates, serum and plasma( heparin).
Target speciesHu
Assay typecomplete kit